Ganglioneuroblastoma

A moderately malignant neoplasm composed of primitive neuroectodermal cells dispersed in myxomatous or fibrous stroma intermixed with mature ganglion cells. It may undergo transformation into a neuroblastoma. It arises from the sympathetic trunk or less frequently from the adrenal medulla, cerebral cortex, and other locations. Cervical ganglioneuroblastomas may be associated with HORNER SYNDROME and the tumor may occasionally secrete vasoactive intestinal peptide, resulting in chronic diarrhea.

Also Known As:

Ganglioneuroblastomas

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Ganglioneuroblastoma: 222
  - Glandular and Epithelial Neoplasms: 439
    - Neuroepithelial Neoplasms: 412
      - Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Ganglioneuroblastoma: 222
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Ganglioneuroblastoma: 222

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Disease

Drug/Important Bio-Agent (IBA)